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Could some medications cause teeth grinding?

  • Writer: kristin Soraya
    kristin Soraya
  • 14 hours ago
  • 2 min read

Have you ever noticed jaw tension, sore teeth, or a dull headache — especially in the morning? If so, you might be grinding your teeth at night, a condition known as bruxism. While stress is a common cause, you might be surprised to learn that some medications can also trigger teeth grinding.

Let’s explore why this happens and what you can do about it.

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What Is Bruxism?

Bruxism is the involuntary grinding, clenching, or gnashing of teeth, often during sleep. It can wear down your teeth, strain your jaw, and even lead to TMJ problems if left untreated.

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The Medication Connection

Certain medications—especially those that affect the central nervous system or brain chemicals like serotonin and dopamine—can increase the risk of grinding. These brain chemicals are involved in regulating muscle movement, mood, and sleep.

When they’re out of balance, it may lead to increased jaw muscle activity, even when you’re asleep and unaware.

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Medications Most Commonly Linked to Bruxism:

1. Antidepressants (SSRIs and SNRIs)

Examples: Prozac (fluoxetine), Zoloft (sertraline), Paxil (paroxetine), Cymbalta (duloxetine), Effexor (venlafaxine)

Why? These medications increase serotonin, which may interfere with dopamine—affecting motor control and muscle tension.

2. ADHD Medications (Stimulants)

Examples: Adderall, Ritalin, Vyvanse

Why? Stimulants activate the nervous system, which can lead to increased tension and muscle clenching.

3. Antipsychotics

Examples: Abilify (aripiprazole), Risperdal (risperidone), Haldol (haloperidol)

Why? These medications also alter dopamine levels, which can affect jaw movement.

4. Certain Sleep Aids or Antiepileptics

These may disrupt normal sleep patterns or muscle control, leading to nighttime grinding.

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Signs You Might Be Grinding Your Teeth

Morning jaw soreness or tightness

Flattened or chipped teeth

Tooth sensitivity

Headaches (especially behind the temples)

Clicking or popping in the jaw

If you’re on any of the medications listed above and experience these symptoms, it's worth talking to your doctor and dentist.

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What Can You Do?

1. Don’t stop your medication without talking to your doctor.

Sometimes switching medications or adjusting the dose can help.

2. Let your dentist know.

At Laguna Hills Family Dentistry, we can check for signs of bruxism and recommend a custom night guard to protect your teeth.

3. Try stress-reduction techniques.

Even when medication is a factor, managing stress can make symptoms better.

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How We Can Help

If you're concerned about grinding, our team is here to help you:

Evaluate your bite and jaw

Look for signs of wear or damage

Fit you with a comfortable, custom night guard to protect your teeth

Work with your physician if a medication might be contributing to your symptoms.


Laguna Hills Family Dentistry . (949)588-7525

24407 Calle De La Louisa Ste. 200 Laguna Hills , CA 92653

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